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Volume 31 , Issue 5
September/October 2011
Pages 535–544

Clinical and Histologic Evaluation of Fresh Frozen Human Bone Grafts for Horizontal Reconstruction of Maxillary Alveolar Ridges

Giovanna Orsini, DDS, PhD/Claudio Stacchi, DDS, MSc/ Erika Visintini, DDS, MSc/Donato Di Iorio, DDS, PhD/ Angelo Putignano, MD, DDS/Lorenzo Breschi, DDS, PhD/ Roberto Di Lenarda, DDS

PMID: 21845248
DOI: 10.11607/prd.00.1010

The aims of the present study were to clinically and histologically evaluate human fresh frozen bone (FFB) grafts used to treat severe maxillary horizontal defects prior to dental implant placement. Ten patients were treated with FFB onlay grafts. Measurements using computed tomography scans were recorded preoperatively and at 5 months. Six core biopsies were retrieved and processed for light microscopy. At baseline, thickness of the maxillary alveolar ridge measured 2.3 ± 0.4 mm; it measured 6.8 ± 0.5 mm after reconstruction. All implants were successful after 24 months. Histologic results showed that FFB blocks and new bone were integrated perfectly. Histomorphometry revealed a mean percentage of bone of 57.5% ± 24.7%. (Int J Periodontics Restorative Dent 2011;31:535–544.)

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